Want to learn more about Cushing's disease?
ShineOut is an education & support program to help manage Cushing's disease
Cushing's disease is a form of Cushing's syndrome and has the same signs and symptoms
Since Cushing's disease is a form of Cushing's syndrome, many of the signs and symptoms of Cushing's disease are the same as those for Cushing's syndrome. In order to determine whether you have Cushing's disease, your doctor will follow a diagnostic process that is explained in more detail in the How Cushing's disease is diagnosed section of www.CushingsDisease.com.
Cushing's disease can affect everyone differently. Not only do people experience different symptoms, but the severity of symptoms can also vary. By understanding how Cushing's disease can affect your body, you may be better prepared to discuss and help diagnose your disease with your doctor. Some of the physical symptoms of Cushing's disease are easier to notice than others. Most of these symptoms occur when you have too much cortisol (called hypercortisolism) in your body for too long, and may improve or disappear when your level of cortisol is lowered to normal. Many people who have Cushing's disease don't notice their symptoms right away because they happen gradually.
Tell your doctor about any symptoms you experience and ask if Cushing's syndrome or Cushing's disease could be the cause. If you don't ask, your doctor may not think to look for Cushing's because it is rare and its symptoms resemble those of other conditions.
|Purple or pink striae||Streaking or stretch marks appear on your abdomen, thighs, buttocks, arms, and breasts.|
|Uncontrollable weight gain||You quickly gain weight for no apparent reason (your diet and exercise habits didn't change).|
|Irregular weight gain/fat distribution||You tend to gain weight in specific areas of your body, especially your abdomen and neck.|
|Buffalo hump||Unusual buildup of fatty tissue between the shoulder blades that creates a hump.|
|Acne/facial redness (purpura)||More frequent appearance of pimples, blemishes, or redness on your face.|
|Hair growth (called hirsutism)||If you are a woman, excessive hair grows on your face and/or body.|
|Moon face||Your face becomes rounded, especially around the jaw area.|
|Menstrual changes||If you are a woman, your menstrual periods become irregular or even stop.|
|Bruising and poor wound healing||Your skin becomes fragile and thin so that it bruises more easily and takes a longer time for wounds to heal.|
|Weakness||Your muscles seem to get smaller and you have difficulty with common activities like climbing stairs or rising from a seated position.|
|Fatigue||You are often tired or tire more easily from common activities.|
|Decreased libido||You are less interested in having sex.|
|Sleep disturbances||You begin having trouble falling asleep or you wake up during the night.|
|Cognitive deficits||You have difficulty paying attention, remembering, and/or understanding things.|
|Weak or brittle bones (called osteoporosis)||Your bones' ability to absorb calcium and repair are affected by hypercortisolism. As a result, you have backaches and rib or spinal column fractures from routine activities such as bending, lifting, or rising from a chair.|
|High blood pressure (called hypertension)||Your body's blood flow is causing too much pressure against artery walls.|
|High blood sugar (called hyperglycemia)||Your body has difficulty processing sugar, and blood sugar levels become higher than normal.|
|High cholesterol and triglycerides||The amount of cholesterol and triglycerides build up in your arteries, raising your risk of heart disease.|
|Excess blood clotting||Your blood forms unneeded clots (soft, thick masses of blood that form to prevent too much bleeding) that can limit or block blood flow and damage your body.|